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- Horizontal wrinkles on the forehead
- Deep interbrow wrinkles
- Wrinkles at the corners of the eyes (“crow's feet”)
- Nasolabial wrinkles
- “Pouch wrinkles”
- Lowering of the corners of the mouth
- Asymmetry of the face
- Hyperhidrosis
- Pregnancy and lactation
- Diseases of the muscular system (e.g. myasthenia gravis)
- Allergy to botulinum toxin
- Acute infectious processes in the injection area
- Exacerbation of skin diseases
- Oncological diseases