- Wrinkles and creases
- Pigment spots
- Scars, scars, stretch marks
- Acne, post-acne
- Skin ptosis
- Dark circles and bags under the eyes
- Reduced skin tone
- Acute infectious or viral diseases
- Acute period of herpes
- Oncological disease
- Pregnancy and lactation
- Anticoagulant therapy
- Blood diseases
- A large number of inflammatory elements on the skin