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- Skin sagging as a result of natural changes
- Thin and inexpressive lips
- Deep wrinkles, creases
- Asymmetry of the face or lips
- Expressed nasolabial folds
- Post-acne, scars
- Loss of skin elasticity and volume
- Patient's own desire for change and improvement
- Pregnancy and lactation
- Inflammatory diseases of the skin
- General acute diseases
- Oncological diseases
- Diseases of the blood
- Autoimmune diseases
- Medication - e.g. anticoagulants
- Allergic reactions to drug components